Chronopharmacokinetics of Methotrexate in Mice: Modulation by Administration of 5-Fluorouracil in Combination Chemotherapy

The basic pharmacokinetic parameters of MTX administered as Label Console Window monotherapy as well as in the combined therapy with simultaneous and prior administation of FU were investigated.The parameters were determined in the two-compartment open system on the basis of measurement of MTX levels in mice after i.p.administration of a single dos

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Two models of the capacitated vehicle routing problem

The aim of the Capacitated Vehicle Routing Problem (CVRP) is to find a set of minimum total cost routes for a fleet of capacitated vehicles based at a single depot, to serve a set of customers.There exist Water Bottles various integer linear programming models of the CVRP.One of the main differences lies in the way to eliminate sub-tours, i.e.cycle

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Amniotic membrane can be a valid source for wound healing

Hossam ElHeneidy,1 Eman Omran,1 Ahmed Halwagy,1 Hesham Al-Inany,1 Mirvat Al-Ansary,2 Amr Gad3 1Department of Obstetrics & Gynecology, 2Department of Clinical Pathology, 3Department of Surgery, Faculty of Medicine, Cairo University, Cairo, Egypt Abstract: Amniotic membrane (AM) can promote proper epithelialization with suppression of excessive f

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